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That might mean focusing more on lifestyle changes, switching medications, or considering bariatric surgery. For some patients, surgical options such as sleeve gastrectomy may be appropriate, particularly if they want a more durable intervention

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PubMed Central, Diz-Chaves, Yolanda, et al

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Theres no hard and fast rule but, if bone loss is one of your issues, either due to age, menstrual status, sedentary lifestyle, or poor diet, it is recommended that you try to fatigue in 10-12 repetitions