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Scientific Reports, 9(1), 9772

The AANAT variant rs28936679 is a rare variant that causes delayed phase sleep disorder.[ref] TPH2 Gene: The TPH2 gene codes for the rate-limiting enzyme involved in the conversion of tryptophan to serotonin, which can then be converted to melatonin

The researchers of this study were based at the University of Bergen in Norway, conducting the study completely independent of any commercial interest

These functional protective effects are consistent with metaproteomic findings in children with recent-onset T1D (188), where gut microbiota dysregulation (including reduced butyrate-producing taxa) correlates with -cell damage severity, supporting a clinical link between butyrate deficiency and T1D pathogenesis

to eliminate all of them through urine and bile, as part of its detoxification process