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Because of this, the different gas treatments that comprise a single experiment cannot be performed in adjacent wells of a 96-well plate
That rationale must be backed by non-clinical data confirming the compound behaves as expected and by a thorough safety and toxicology program that identifies potential risks and establishes a safe starting dose for the first human administration and the maximum human exposure that should not be surpassed
133 In human trials, the prebiotic fibers inulin and dextrin induced reductions in serum levels of total cholesterol (-9% and -2% for inulin and dextrin, respectively), LDL cholesterol (-1 % for dextrin), and triglycerides (-21% for inulin)
The first 30 infusions are delivered on a weekly basis and the last 10 are delivered during a maintenance phase every two to eight weeks
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