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Cancer Lett 430:133147 Hammouda MB, Ford AE, Liu Y, Zhang JY (2020) The JNK signaling pathway in inflammatory skin disorders and cancer

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For a deeper standalone breakdown, see What Is MOTS-c

If disrupted, permeation of potentially noxious molecules and organisms from the intestinal lumen can result in a cascade of events including immune activation and inflammation, eventually triggering the development of intestinal and systemic diseases (Fig