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Metabolic instruction of immunity

Agonists, such as (Val8) GLP-1, showed a clear upregulation of LTP in area CA1 of the hippocampus, while the selective GLP-1R antagonist exendin (936) blocked LTP

As regular readers of these pages will recall, the term incretins refers to a group of gut hormones that elicit a wide range of biological actions affecting ingestive behaviour, gut function and metabolic control

Ghaffarian R, Herrero Edgar P, Oh H et al (2016) Chitosan-alginate microcapsules provide gastric protection and intestinal release of ICAM-1-targeting nanocarriers, enabling GI targeting in vivo

Meanwhile, it is primarily found in the brain and retina and is an endogenous scavenger for free radicals