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Like many popular weight loss medications, retatrutide works by acting on hormone receptors in tissues throughout the body

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Short chain fatty acids stimulate the production of GLP-1 and other hormones that regulate hunger such as peptide YY (PYY) and cholecystokinin (CCK) which may help reduce excess calorie intake without the side effects and cost of weight loss medications

The tri-phasic metabolic obesity framework: a staged approach to synergizing glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and metabolic surgery

This implies that Satb2-positive cells, including goblet cells, absorptive cells, and enteroendocrine cells, might be involved in the regeneration of the colonic mucosa