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A direct detrimental incretin effect on the central nervous system could also be hypothesized and susceptible people receiving GLP-1 RAs may, in some circumstances, experience a worsening of hedonic tone predisposing psychopathology and/or self-harm ideation and/or other aspects of suicidality

David Nazarian a board-certified internal medicine physician trained at UCLA, the Sackler School of Medicine, and Huntington Memorial Hospital, a USC-affiliated teaching institution with dosing, frequency, and candidacy determined through individual clinical assessment

Chancey JH et al (2014) Hilar mossy cells provide the first glutamatergic synapses to adult-born dentate granule cells

The best area to get a B12 shot is in the upper area of the gluteus medius muscle, just above the buttocks in the hip region