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Dariush Mozaffarian 1, Monica Agarwal 2, Monica Aggarwal 3, Lydia Alexander 4, Caroline M Apovian 5, Shagun Bindlish 6, Jonathan Bonnet 7, W Scott Butsch 8, Sandra Christensen 9, Eugenia Gianos 10, Mahima Gulati 11, Alka Gupta 12 13, Debbie Horn 14, Ryan M Kane 15 16, Jasdeep Saluja 17, Deepa Sannidhi 18, Fatima Cody Stanford 19 20, Emily A Callahan 1
Its an agonist for three key receptors involved in metabolism and appetite regulation: Glucagon-like peptide-1 (GLP-1): This is the well-known pathway targeted by drugs like semaglutide
Save more intense cardio for after reaching maintenance phase
The treatment of type 2 diabetes requires positive modulation of GLP-1R to inhibit glucagon secretion and stimulate insulin secretion in a glucose-dependent manner 2
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