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Unlike GHRP-6 and hexarelin, which increase cortisol, prolactin, and appetite alongside GH release, ipamorelin is reported to produce GH release with minimal off-target hormonal effects, which is why it has become a preferred pharmacological tool for isolating GH-axis effects from cortisol and prolactin-related confounders in experimental design

De Sandre-Giovannoli, A

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