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Expert opinions vary

Sedation agents need to be adjusted because of the risk of accumulation in case of altered liver function and/or renal function

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Ultraviolet radiation can still damage DNA, accelerate photoaging, and increase skin-cancer risk

15 The gene for glutathione peroxidase-4 is expressed in most tissues, including the brain (Gene Expression Atlas, available at Although the GPX4 gene is highly polymorphic, a limited number of studies 16, 17, 18, 19 have been done to investigate genetic variations within the GPX4 gene that could potentially alter the function of the enzyme