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LV, Left ventricular

Notably, anlotinib also has been shown to suppress the extracellular regulated kinase ( ERK ) signaling pathway and reverse the epithelial-mesenchymal transition (EMT) process in various tumor models (25)

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Research has explored whether NNMT inhibitions effects extend beyond direct enzyme activity to broader metabolic reprogramming, including observations of altered mitochondrial function, lipid oxidation, and gene expression in research models

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