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Effects of GLP-1R activation in the heart The observation that GLP-1 decreases contractility in primary culture of adult rat cardiomyocytes, despite increasing cAMP levels, [38] has also been reported in isolated rat hearts [45]

While generally safe for healthy individuals, probiotics can cause bloating, gas, and gastrointestinal discomfort

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GLP- 1 Receptor Agonists for the Treatment of Obesity Liraglutide Liraglutide at a high dose of 3 mg daily is approved for long-term weight control in adults and children over the age of 12 with obesity or overweight plus at least one weight-related comorbidity