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The crosstalk between insulin and renin-angiotensin-aldosterone signaling systems and its effect on glucose metabolism and diabetes prevention

While ruminants can synthesize B 12 via gut bacteria if soil cobalt levels are adequate, monogastric animals like swine and poultry require direct supplementation through fortified feed to maintain health and growth rates in intensive farming environments

These metabolite changes suggest that the retrograde signal may involve altered activity of chromatin-modifying enzymes sensitive to these metabolites

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PMID: 72 DingHZhangJZhangFZhangSChenXLiangWet al