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Zara Cosentino, commenting on the panel's composition, said that while the disclosure of conflicts is a positive transparency measure, it creates a structural problem: "especially when the people who stand to gain from growing access are the ones making the decision." Advisory meetings are subject to federal transparency requirements experts with financial stakes may serve, but relationships must be disclosed and the FDA is expected to explain why the panelist's expertise outweighs the conflict

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In some embodiments, an otic composition or formulation disclosed herein comprises less than about 50 ppm of each of C1-C4 alcohols or C1-C4 glycols