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It accomplishes this through several distinct mechanisms: Collagen and elastin stimulation: GHK-Cu upregulates the genes responsible for collagen I, collagen III, and elastin synthesis the structural proteins that give skin its firmness, bounce, and thickness

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Collectively, these data indicate that iron-dependent fur- regulated genes contribute to longer and more severe infections by regulating iron within the cell ( The ability to acquire specific haem sources may also be linked to the pathogenic potential of NTHi isolates

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