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Quality of weight loss (body composition): evidence suggests a greater reduction in fat mass, without a disproportionate increase in lean mass loss, in body-composition sub-studies

Practical strategies that help: Practice the motions with an empty syringe or water draw before your first real dose Ice the site for 3060 seconds beforehand to dull sensation (check with your provider first) Breathe slowly-inhale for four counts, exhale for four, and inject on the exhale Use distraction: music, a podcast, counting backward from ten Schedule your first dose when youre unhurried and calm, not squeezed between meetings Having a trusted person present-in the room or on a video call-can provide real emotional support

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In scientific updates, a new study (GLP-1 Receptor Agonists or SGLT2 Inhibitors and Nonarteritic Anterior Ischemic Optic Neuropathy) suggests that taking a GLP-1 may be associated with an increased risk of developing NAION, a type of eye stroke that can cause sudden, permanent blindness

The injection site can be the thigh, abdomen, or upper arm