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There is no human trial of this exact combination, so the evidence here is built from studies on the individual components, most of it preclinical

BPC-157 is a synthetic 15-amino-acid peptide derived from a partial fragment of body protection compound, a protein found in human gastric juice

In both studies, the mode of supplementation was via injection, which tends to involve high doses of vitamin B12, although precise dosages were not specified

Seven Signs That Suggest Low B12 These signs do not appear all at once

The researchers surmised that the typical reduction of glutathione in the elderly was due to a lower supply of glycine and cysteine, the precursors to glutathione synthesis, and that upon supplementation, they had the ability to stimulate synthesis and restore levels