Exosomes, or extracellular nanovesicles, and peptides, small strings of amino acids, have shown promise as topical therapies in early trials, but neither is FDA approved
However, N-terminal modifications, such as N-acetylation, D-norleucine substitution, or replacement with -aminobutyric acid (GABA), dramatically elongated the peptides half-lives
Recent bioinformatic studies have further underscored its clinical relevance by highlighting a pronounced cuproptosis signature in myocardial infarction, involving key regulators such as SLC31A1 and ferredoxin-1 (FDX1) [42]
The Face Cream and GHK-Cu Serum smooths and firms the skin, the Hair & Scalp Serum nourishes the scalp for a healthy hair environment
It also has anti-inflammatory properties, reducing redness and irritation, which is beneficial for sensitive skin