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Practical approaches include: sipping fluids throughout the day rather than drinking large volumes at once, choosing beverages with electrolytes when experiencing gastrointestinal symptoms, and setting reminders to drink regularly

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These strategies highlight the potential of GSH-responsive nanomedicine as part of integrated, multi-modal cancer treatments

In addition, mtROS can also directly act on some proteins on the mitochondrial matrix or mitochondrial membrane, and regulate the activity of mitochondrial complex I, complex III, and complex IV through Toll-like receptors, retinoic acid-inducible gene I-like receptors and other signaling pathways, thereby affecting OXPHOS