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The introduction of wortmannin was found to significantly reverse the expression of PI3K and AKT, as well as the anti-apoptotic and anti-inflammatory effects of Dihexa, resulting in a decrease in the number of neuronal cells present in the cortex and the levels of IL-10, and an increase in the levels of TNF-alpha and IL-1-beta [1]

For the purpose of this study, 10 to 12 week old inbred male Lewis rats weighing approximately 300 grams each were used

Dihexa Based on 6 publication(s) in Google Scholar Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog

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