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Based on his comparisons of blood vessels of patients who died from cardiovascular disease versus other causes Dr

These included: Nausea (most frequently reported) Vomiting Diarrhoea Constipation Decreased appetite These effects were generally dose-dependent and transient , tending to occur during the dose escalation phase and resolving or diminishing over time

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Caution is also advised for patients with a history of pancreatitis, gastroparesis, diabetic ketoacidosis and hypersensitivity reactions