While it lacks the specific FDA approval of Wegovy, compounded semaglutide can still provide significant benefits for weight loss, assuming its sourced from a reputable compounding pharmacy
Another approach is to quantify current GLP-1 utilization and cost (including use for treating T2DM)
Thereaux J, Lesuffleur T, Pata M, et al
In one trial, adults with obesity and diabetes taking the drug lost up to an average of 20.8% of their weight, or nearly 50 pounds, at 80 weeks
While dexamethasone only modestly reduced synovial inflammation, it failed to prevent cartilage deterioration, whereas liraglutide significantly enhanced pain thresholds, lowered synovial scores, and preserved cartilage integrity, with 60 g doses notably reducing overall joint damage [140]