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Description

SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis

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N gip chng li tc hi bc x c th xy ra da, vng mc, gic mc, Nh duy tr ln da gim np nhn, tng s tr trung, y sc sng

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investigational only

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Acid-cleavable linkers [1] Disulfide bonds represent another critical category of chemically cleavable linker s (Figure 4), utilized in three approved ADCs (Mylotarg, Besponsa, and Elahere)

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J.LengY.et al

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