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A total of 8554 genes presenting a significantly positive ( n = 4572) or negative ( n = 3982) correlation with aging were selected for further analysis

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The consumption and absorption of these important trace minerals may decrease with aging

The dynamic balance between DNA methyltransferases and TET enzymes functions as a critical regulatory axis, shifting astrocyte gene expression profiles from homeostatic maintenance toward neuroinflammation and neurodegeneration-promoting states

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