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Direct mechanisms of tirzepatide on cardiovascular health Although the precise mechanism by which tirzepatide could benefit HF is not known, several potential pathways have been suggested: Anti-inflammatory effects Patients with T2DM experience increased levels of hyperinsulinemia, hyperglycemia, and insulin resistance

GLP-1 medications, used for weight loss and diabetes, may indirectly cause temporary hair loss, potentially due to rapid weight loss stressing hair follicles

32 Furthermore, subsequent large retrospective studies have demonstrated no effect of GLP-1RA on the increased risk of ischemic optic neuropathy

Dong, M., Koole, C., Wootten, D., Sexton, P

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