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The most frequently reported adverse events were gastrointestinal in nature, including nausea (occurring in 25-33% of patients), diarrhea, vomiting, constipation, and abdominal discomfort
In fact, in a recent survey from Business Group on Health, 96 percent of employers said they worry about the long-term cost implications 1
These symptoms may occur, but they should not automatically be classified as detox symptoms
Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-1 in rat glomerular messangial cells