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Rofeal et al., 2022), as well as fungi (Poznanski et al., 2023

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The autoinjector device is widely considered the simplest to use among all GLP-1 medications, and the cardiovascular outcome trial (REWIND) demonstrated significant reduction in major adverse cardiovascular events

The risk of developing these severe side effects is very small, but it is important that patients and healthcare professionals are aware and alert to the associated symptoms. An estimated 1.6 million UK adults used GLP-1s such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro) to lose weight between early 2024 and early 2025, with an additional 3.3 million interested in using weight loss drugs during 2026