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Enemas were also effective in 5 trials on over 250 children, but didnt have any added benefits to laxatives in another one on 100 children [11, 12, 13, 14, 15, 16]

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Appl Environ Microbiol 2007

Importantly, this catalytic tetrad is conserved among all the seleno-GPxs (GPx1, GPx2, GPx3, GPx4, and GPx6) characterized from human (Table 1