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We propose some pathophysiological mechanisms leading to increased cardiovascular and all-cause mortality after infection with SARS-CoV-2 in patients with diabetes mellitus (Fig

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A final alternative to alleviate FcRn-controlled pathological mechanisms could be to alter FcRn in itself, as may be intended with a gene therapy being developed in a collaboration between Beam and Apellis for a one-time dose of gene-editing molecules targeting FcRn [436, 437]