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The dermal collagen pool has begun to decline but matrix architecture is largely intact

Exposure and Response Prevention (ERP): For autistic individuals with significant anxiety or OCD-type behaviours, Exposure and Response Prevention a specific CBT technique is used to systematically and gradually confront feared situations whilst resisting the urge to engage in avoidance or compulsive behaviours

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Structural characterization of flexible proteins using small-angle X-ray scattering