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In a randomised controlled trial with over 1800 participants comparing tirzepatide to semaglutide, the tirzepatide group reported more serious adverse events (5-7% VS 3%) and higher discontinuation rates due to adverse events (6-8.5% VS 4%)

That being said, its worth noting that GLP-1s may actually be beneficial for IBD patients who are stable, since weight loss can lessen inflammation, which can worsen symptoms of these conditions, Holly Lofton, MD, clinical associate professor of medicine and director of the Weight Management Program at NYU Langone Health, tells SELF

Further longer term studies of normal and genetically modified rodents are clearly warranted

What is the difference between research grade and lab grade GLP-3RT

How can Semaglutide GLP-1 benefit your medical weight loss journey with Dr