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Moreover, it has been shown that hyperuricemia (also observed in our study) can cause significant changes in systemic and renal hemodynamics, which may result in the loss of autoregulatory kidneys function 54

10.1073/pnas.1010529108 181 Heintz-BuschartA.PandeyU.WickeT.Sixel-DringF.JanzenA.Sittig-WiegandE.et al

Individual results vary based on starting weight, dose, nutrition, movement, and adherence

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