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NICE guidance recommends tirzepatide for eligible adults with obesity and at least one weight-related comorbidity

Food and Drug Administration (FDA) approval, a quiet but consequential war is already being fought over who gets to manufacture it

Drugs that are essentially copies of commercially available or FDA-approved drugs, unless the drug appears on the FDA drug shortage list (see exception in next bullet)

Roche with its 2024 acquisition of Carmot, and Pfizer, following its 2025 acquisition of Metsera, enter obesity and broaden their presence in cardiovascular/metabolic, while other large pharmaceutical companies prepare to follow later in the decade

These findings support the previous notion that the effect of fat on gastric emptying and absorption of nutrients depends on when it is consumed [150]