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10.3389/fmed.2024.1410668 86 MackowiakB.FuY.MaccioniL.GaoB

If you are currently on semaglutide or compounded tirzepatide , switching to retatrutide means moving to a research-stage compound with less long-term safety data

Take loperamide (Imodium) 2 mg as rescue for acute episodes, up to 8 mg per day

In a 2024 review of three peptides, the FDA noted side effects like increased heart rate, chest tightening, headache, nausea, diarrhea, and elevated liver enzymes, as well as skin irritation and pain at the injection site