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On August 18, the Food and Drug Administration (FDA) granted accelerated approval of Wegovy (semaglutide), in conjunction with a reduced-calorie diet and exercise, for people with metabolic dysfunction-associated steatohepatitis (MASH) who have moderate to advanced liver fibrosis but have not yet developed cirrhosis
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However, both medications can have effects on overall health that need to be carefully monitored
The TRIUMPH-4 result of 28.7 percent at 68 weeks confirms what the Phase 2 curve already suggested: weight loss on retatrutide had not plateaued at 24 weeks
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