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Universal discontinuation may disproportionately affect patients with diabetes, limited access to prescribers, difficulty rescheduling procedures, or high medication costs

Binding of GIP to its receptor also stimulates glucose-dependent insulin secretion and produces a greater proportion of the incretin effect than GLP-1 (about 45% for GIP and 29% for GLP-1) [133]

The ideal approach is to take the injection on the same day each week

13 These findings suggest that supporting gut health with probiotics, prebiotics, and fiber may indirectly enhance GLP-1 activity and overall metabolic function

Others are specifically approved for chronic weight loss treatment in people who meet clinical criteria