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There is increasing interest in developing tripeptides with targeted therapeutic functions, particularly for applications in wound healing [36, 75, 92], as well as in cancer [60, 170], neurodegenerative [24, 173], and cardiovascular diseases [177, 178], and in the design of functional foods [179, 182, 188]

Various plant species synthesize phytochemicals, including tannins, terpenes, isoflavonoids, saponins, and steroids, which exhibit ovicidal, larvicidal, adulticidal, and related bioactivities against insect pests

It was first developed for the treatment of ulcerative colitis and, as of late 2023, is in phase 2 clinical trials to evaluate whether it is also useful for the treatment of EoE

To reduce the number of steps in a sample preparation procedure a simultaneous reduction of disulfide bound with tris(2-carboxyethyl)phosphine (TCEP) and the selective pre-column derivatization of the thiol group with 1-benzyl-2-chloropyridinium bromide (BCPB) has been applied

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