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J Exerc Nutr Biochem

Other factors that influence the liver morphology are: body weight loss, blood flow, food intake, vascular and hemodynamic changes, timing and duration of exposure, withdrawal effects, and functional heterogeneity

Although the BEACON study showed a significant increase in eGFR by 5.5 mL/min/1.73 m 2 in the group treated with 20 mg/day CDDO-ME, this clinical trial was terminated in 2012 because of the high incidence of cardiovascular events, especially heart failure, in the group treated with CDDO-ME (Table 3) [16]