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The 2022 American Society for Metabolic and Bariatric Surgery and International Federation for Surgery and Other Therapies for Obesity guidelines 29 recommend metabolic-bariatric surgery for patients with MASLD or MASH whose body mass index is 30 kg/m 2 or higher who do not achieve substantial weight loss with nonsurgical methods

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They also had higher levels of genes and proteins linked to inflammation and pulmonary fibrosis than people without diabetes

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