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In this trial, at 60 weeks, the exenatide group showed a significant improvement in MDS-UPDRS Part III scores compared to the placebo group among the 62 recruited patients (80)

10.4103/jrms.JRMS_236_20 Summary Keywords L-carnitine, glycemic markers, systematic review, meta-analysis, adult, diabetes mellitus type 2 Citation Zamani M, Pahlavani N, Nikbaf-Shandiz M, Rasaei N, Ghaffarian-Ensaf R, Asbaghi O, Shiraseb F and Rastgoo S (2023) The effects of L-carnitine supplementation on glycemic markers in adults: A systematic review and dose-response meta-analysis

(October, 2016)

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Based on the results of these clinical trials, Novo Nordisk submitted a new drug application for Semaglutide to the US Food and Drug Administration (FDA) in 2017 and was approved for marketing at the end of 2017