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This effect is crucial for sustainable weight loss and long-term health outcomes

What does a provider evaluate before putting these two together

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A Comparison of Mortality in People Initiated With Metformin or Sulphonylurea Monotherapy and Matched, Non-Diabetic Controls

Most notably, a series of large-scale cardiovascular outcome trials (CVOTs) created robust clinical evidence for the cardiovascular benefits of GLP-1RAs in patients with T2DM and high cardiovascular risk or established atherosclerotic cardiovascular disease (ASCVD) [1, 2]