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Minoxidil also upregulates VEGF, but through a different pathway: potassium channel opening and prolyl hydroxylase inhibition (Lachgar et al., 1998)

Research peptides are peptides supplied exclusively for laboratory investigation rather than clinical use

The dosing regimen varies depending on whether neurological symptoms are present: With neurological involvement: 1 mg intramuscularly on alternate days until no further improvement, then 1 mg every 2 months [3] [4] Without neurological involvement: 1 mg intramuscularly three times a week for 2 weeks, then 1 mg every 2-3 months for maintenance [3] [4] There is some evidence that high-dose oral B12 (1000-2000 micrograms daily) may be effective even in some malabsorption conditions, though UK practice still generally favours intramuscular treatment in these cases

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