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Biochem Pharmacol 64:104956, PMID: 12213604 Poole LB, Karplus PA, Claiborne A (2004) Protein sulfenic acids in redox signaling

The importance of glutathione for the management of reactive oxygen species and the link between low glutathione and a variety of conditions have led to the product being studied for an extremely wide range of indications including Parkinsons disease, cystic fibrosis, autism spectrum disorder (ASD), and hyperpigmentation among others

In the context of cardioprotection, low doses of Withaferin A activate AMPK, which shifts the balance of the Bcl-2 protein family toward anti-apoptotic members

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