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It is also being explored for conditions like inflammatory bowel disease (IBD), including Crohns disease and ulcerative colitis, as well as irritable bowel syndrome (IBS), though with mixed results

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This descriptive systematic review aims to provide an overview and discussion of the targeting ligands that have been employed so far to direct intravenously administered non-viral vectors based on lipid carriers, for protein-coding nucleic acid (plasmid DNA (pDNA) and mRNA) supplementation to clinically relevant organs in the treatment of FD

In this scenario, the risk-benefit discussion is the standard one, plus the additional considerations around muscle loss and bone health that weve covered above

Another challenge I faced was dealing with the occasional side effects