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However, sample preparation is somewhat complicated, surface counting is not possible, and it is no longer commercially available ( 17 )

Another option is emerging

Green synthesis of gold nanoparticles and their emerging applications in cancer imaging and therapy: a review

This reduces pigmentation and helps even skin tone

Briefly, to verify the targeted binding between miR-29b-3p and the GGCT gene, a 2000-bp DNA fragment (derived from the transcription start site of the GGCT gene) was inserted into the pmir-GLO-Basic vector to construct the wild-type pmir-GLO-GGCT-3 UTR reporter plasmid (wt) and the mutant pmir-GLO-GGCT-3 UTR reporter plasmid (mut)