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1 Compared with non-RBD-PD patients, those with RBD-PD exhibit increased abundances of opportunistic pathogens (e.g., Aerococcus ) and decreased abundances of beneficial taxa (e.g., Butyricicoccus and Faecalibacterium )

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#These authors contribute equally to this work

The Peptide-treated group exhibited a 15% reduction in both food intake and body weight at 8 weeks, though these effects were reversed after pump removal