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It should be noted that PTU was widely used in the past in an attempt to treat alcohol-induced liver complications and severe alcoholic hepatitis.70,71 However, the beneficial effects of PTU against alcoholism appeared quite limited.70,71 Since alcoholism and alcohol-induced liver injury is an inflammatory-mediated process at least in part,72 one may argue that PTU might hasten liver injury in these patients

10.3390/molecules23020011 250 ZengX.ChenX.QinH.HanY.ChenX.HanZ.et al (2020b)