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5B, C), although the Nrf2 gene was less efficiently deleted compared to the deletion of Gclc

[U- 13 C]glutamine isotope tracing experiments showed that GGCT overexpression reduced Gln contribution to the TCA cycle and diverted it preferentially to the GSH synthesis pathway for ROS regulation

TomitaKTakashiYOuchiYKuwaharaYIgarashiKNagasawaTet alLipid peroxidation increases hydrogen peroxide permeability leading to cell death in cancer cell lines that lack mtDNA

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