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An improved method for delivery of glutathione, a major intracellular antioxidant, by oral administration of S-acetyl-glutathione (SAG) is provided

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It was developed as a highly selective agonist of the growth hormone secretagogue receptor (GHS-R1a, also known as the ghrelin receptor)

& Thomas, C

High extracellular concentrations of glutamate, another raw material for glutathione synthesis, can inhibit system ( SLC7A11 ) and induce iron-dependent non-apoptotic cell death, which may explain the toxic effect of excessive glutamate accumulation in the nervous system (Yang and Stockwell, 2016