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Kidney Disease Management: In January 2025, the FDA approved semaglutide to reduce the risk of worsening kidney disease and cardiovascular death in adults with type 2 diabetes and chronic kidney disease

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Meghan Garcia-Webb, MD, who is triple-board-certified in internal medicine, lifestyle medicine and obesity medicine, shares her insights on meal timing: We dont have enough evidence to make any firm conclusions about direct effects of meal timing on medication efficacy, but there is a small but growing body of research to suggest circadian rhythm impacts weight. So, for those looking to optimize their dietary habits, finishing meals by early evening might sync better with the bodys natural rhythms, potentially enhancing the effectiveness of their weight loss regimen

Severe insulin resistance associated with conditions like non-alcoholic fatty liver disease (NAFLD) or metabolic syndrome may require higher semaglutide doses or combination therapy to overcome

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